Which nation gave the Romans the most military problem? One of the nations that gave the Romans the most military problem was the ancient area of Carthage. Carthage was a important megacity- state located in North Africa, near present- day Tunisia. The conflicts between Rome and Carthage are famously known as the Punic Wars, which took place over several centuries from 264 BC to 146 BC.

During the Punic Wars, Carthage posed a significant challenge to Rome’s military dominance. The most notorious Carthaginian general was Hannibal Barca, who led a enterprising irruption of Italy during the Alternate Punic War. Hannibal achieved several major palms against the Romans, most specially the Battle of Cannae in 216 BC, where he foisted a crushing defeat on a much larger Roman army.

Eventually, Rome surfaced as the victor in the Punic Wars, and Carthage was fully destroyed in the Third Punic War in 146 BC. still, the conflicts with Carthage were some of the most grueling and protracted military juggernauts that the Romans faced in their expansionary sweats.